Robertas Žilinskas

TITLE: Good Laboratory Practices for Proteomics Workflows

Proteomics is the study of all the proteins in a biological system, aiming to understand their functions and roles. This market size is ever growing field which is expected to grow further with increasing rate of clinical diagnostics and drug discoveries. Thanks to technological improvements of mass spectrometry, proteomics reached high sensitivity, accuracy and high throughput across multiple conditions with less sample than western blotting and no antibodies needed. However, with great benefits comes great responsibility. Failed clinical trials may cost additional 0.8-1.4 bn USD per company as only ~30% of candidate drugs advance to phase III trials. For this reason, implementation of good laboratory practice is essential to avoid incomparable results, long troubleshooting phases, rejected publications and unknown status of the experiment. Find out more about QC tools and design valuable to implement in proteomics workflow such as reference materials, system suitability test, control charts troubleshooting ideas and more.